8 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Serenade

DepartsSat, Jun 6th 2026

ReturnsSun, Jun 14th 2026

Nights8

Departing PortMemphis

Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans

Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…

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8 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Heritage

DepartsWed, Jun 10th 2026

ReturnsThu, Jun 18th 2026

Nights8

Departing PortMemphis

Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans

Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season. From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…

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8 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Melody

DepartsSat, Jun 13th 2026

ReturnsSun, Jun 21st 2026

Nights8

Departing PortMinneapolis/St. Paul

Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)

American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…

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8 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Heritage

DepartsWed, Jun 17th 2026

ReturnsThu, Jun 25th 2026

Nights8

Departing PortNew Orleans

Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis

Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season. From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…

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11 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Heritage

DepartsTue, Jun 23rd 2026

ReturnsSat, Jul 4th 2026

Nights11

Departing PortNew Orleans

Ports of CallNew Orleans, Mississippi River, Baton Rouge, Natchez, Vicksburg, Cruising the River, Memphis, Paducah, Cruising the River, St Louis (2 Days)

Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season. From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…

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8 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Heritage

DepartsWed, Jun 24th 2026

ReturnsThu, Jul 2nd 2026

Nights8

Departing PortMemphis

Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans

Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season. From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…

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