14 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Pioneer
DepartsSat, Nov 1st 2025
ReturnsSat, Nov 15th 2025
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Sailing Tolomato River, Saint Augustine, Port Canaveral, West Palm Beach, Key Biscayne, Key West (2 Days), Marco Island, Punta Gorda, St. Petersburg (2 Days)
Experience our brand new American Pioneer, tailored for intimate cruising along the Florida Coast, accommodating just 125 guests. Immerse yourself in comfort and elegance as you traverse the serene waters. Delight in spacious staterooms adorned … 
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Star
DepartsMon, Nov 3rd 2025
ReturnsMon, Nov 17th 2025
Nights14
Departing PortBaltimore
Ports of CallBaltimore, St. Michaels, Norfolk, Kitty Hawk, Beaufort, Wilmington, East Coast Inland Passage, Charleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Fernandina Beach, Jacksonville
The American Star will offer guests the same style of cruising that has become the hallmark of American Cruise Lines. From charming small towns to gracious ports, the American Star will bring guests to places of historic interest and m…
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsWed, Nov 5th 2025
ReturnsWed, Nov 19th 2025
Nights14
Departing PortBaltimore
Ports of CallBaltimore, St. Michaels, Norfolk, Kitty Hawk, Beaufort, Wilmington, East Coast Inland Passage, Charleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Fernandina Beach, Jacksonville
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Glory
DepartsFri, Nov 7th 2025
ReturnsFri, Nov 21st 2025
Nights14
Departing PortBaltimore
Ports of CallBaltimore, St. Michaels, Norfolk, Kitty Hawk, Beaufort, Wilmington, East Coast Inland Passage, Charleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Fernandina Beach, Jacksonville
American Glory blends the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. Observation and sitting areas will be available at the bow, while a unique Swim/Activity Platform at th…
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsFri, Nov 7th 2025
ReturnsFri, Nov 21st 2025
Nights14
Departing PortBaltimore
Ports of CallBaltimore, St. Michaels, Norfolk, Kitty Hawk, Beaufort, Wilmington, East Coast Inland Passage, Charleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Fernandina Beach, Jacksonville
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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14 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Patriot
DepartsMon, Nov 10th 2025
ReturnsMon, Nov 24th 2025
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Sailing Tolomato River, Saint Augustine, Port Canaveral, West Palm Beach, Key Biscayne, Key West (2 Days), Marco Island, Punta Gorda, St. Petersburg (2 Days)
American Patriot offers an intimate and luxurious cruising experience, catering to just 125 guests with a focus on comfort, elegance, and coastal exploration. The interior design of the ship features a serene color palette, creating a tranquil ambian…
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsWed, Nov 19th 2025
ReturnsWed, Nov 26th 2025
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
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7 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsFri, Nov 21st 2025
ReturnsFri, Nov 28th 2025
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Palatka, Lake George, Florida, Green Cove Springs, Sailing Tolomato River, Saint Augustine, Amelia Island, Jacksonville
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsWed, Nov 26th 2025
ReturnsWed, Dec 3rd 2025
Nights7
Departing PortCharleston
Ports of CallCharleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
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7 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsFri, Nov 28th 2025
ReturnsFri, Dec 5th 2025
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Palatka, Lake George, Florida, Green Cove Springs, Sailing Tolomato River, Saint Augustine, Amelia Island, Jacksonville
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
