Save up to $1,000 on select Mississippi River cruises
Offer valid from Friday, July 17th 2026 to Wednesday, September 30th 2026
Details
8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Feb 13th 2027
ReturnsSun, Feb 21st 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis… 
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Feb 17th 2027
ReturnsThu, Feb 25th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Mississippi River, Oak Alley, New Orleans
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsFri, Feb 19th 2027
ReturnsSat, Feb 27th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Feb 20th 2027
ReturnsSun, Feb 28th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Feb 24th 2027
ReturnsThu, Mar 4th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsThu, Feb 25th 2027
ReturnsFri, Mar 5th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Feb 27th 2027
ReturnsSun, Mar 7th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsWed, Mar 3rd 2027
ReturnsThu, Mar 11th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Mar 3rd 2027
ReturnsThu, Mar 11th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Mississippi River, Oak Alley, New Orleans
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Symphony
DepartsThu, Mar 4th 2027
ReturnsFri, Mar 12th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
The 180-passenger American Symphony introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography acro…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Mar 6th 2027
ReturnsSun, Mar 14th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsTue, Mar 9th 2027
ReturnsWed, Mar 17th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
Call for pricing
Outside
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Mar 10th 2027
ReturnsThu, Mar 18th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
Inside Cabin
Call for pricing
Outside
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Mar 13th 2027
ReturnsSun, Mar 21st 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsMon, Mar 15th 2027
ReturnsTue, Mar 23rd 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
Call for pricing
Outside
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Mar 17th 2027
ReturnsThu, Mar 25th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Mississippi River, Oak Alley, New Orleans
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
Inside Cabin
Call for pricing
Outside
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Mar 20th 2027
ReturnsSun, Mar 28th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
Outside
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsSun, Mar 21st 2027
ReturnsMon, Mar 29th 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
Call for pricing
Outside
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Splendor
DepartsWed, Mar 24th 2027
ReturnsThu, Apr 1st 2027
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
American Splendor, formerly America, will receive a total redesign, allowing our guests to experience the nostalgia of classic paddlewheeler travel, while enjoying perfect comfort and the most modern amenities.American Splendor will be completel…
Inside Cabin
Call for pricing
Outside
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Mar 27th 2027
ReturnsSun, Apr 4th 2027
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
Outside
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
Terms and Conditions:
Booking Window: 7/17/26 - 9/30/26
Applicable Sailings: Lower Mississippi River cruises departing from Feb - April 2027. 9 days/8 nights Memphis to New Orleans (reverse itineraries available)
Terms & Conditions: *Savings per stateroom are based on limited availability. Certain restrictions apply. Ship, itinerary, savings, and schedules are subject to change. Reverse itineraries available. Free airfare and savings on select dates. Valid on new bookings only.
